Metabolomics is a newly emerging field concerned with the comprehensive characterization of low-molecular-weight metabolites in biological systems. The metabolomics core laboratory focus on explore the aging related biomarker by metabolomics method. Information obtained from metabolomics approach may provide a global view of the metabolic pathways, network, and their interactions in normal and pathophysiological states. Accordingly, metabolomics-based information may help to detect disease progression, monitor response to treatment. Since a global metabolomics is most applicable to human degenerative diseases including diabetes, cardiovascular disease, and neurodegenerative diseases, which involve the interactions of multiple risk factors in disease pathogenesis and progression. Metabolomics approach relies on nuclear magnetic resonance spectroscopy and mass spectrometry as the key tools for untargeted metabolite profiling and target metabolite identification. Plasma, urine, CSF, cells and biospecimens are samples for analysis.
1. Biosensing for the applications in healthy aging and biomolecules
2. Cancer studies with optical imaging modalities